Cas9 Antibodies
GenCrispr/Cas9 Genome Editing Products
CRISPR/Cas9 technology is a powerful technique that has revolutionized the field of sequence-specific gene editing due to it's high precision, simplicity and flexibility. The CRISPR/Cas9 system consists of two major components: the Cas9 nuclease and the sequence-specific guide RNA (gRNA). They can form a very stable ribonucleoprotein (RNP) complex. Once a specific DNA region is matched by the gRNA carrying Cas9, the target DNA is cleaved with a double stranded break. Cas9 RNP complex can be introduced into cells directly and act immediately after it enters the cell without transcription and translation. By matching the gRNA sequence with different functional domains, the CRISPR/Cas9 system and its variants have been used for a broad range of gene editing applications (knock-out, knock-in, gene up/down, genome purification and visualization et. al.).
GenScript offers multiple kits to assemble your own Cas9 and gRNA constructs, as well as purified Cas9 enzymes for in vitro and in vivo use.
GenCrispr Cas9 Antibodies
CRISPR/Cas9 system is a powerful gene editing tool to modify target genes. Successful applications of the CRISPR Cas9 technology have been reported across single cell and multi-cell organisms, from human cells to plants such as maize and cotton. The approach is simple to implement using the Cas9 enzyme and a gRNA molecule, and can be applied in a DNA-free system. The Cas9 enzyme originating from Streptococcus pyogenes (SpCas9) is the most widely studied, and Cas9-specific antibodies are used to ascertain enzyme expression.
Key applications:
Western Blotting / FACS / ELISA / IHC
Cat. No. |
Product Name |
A01957-40 |
|
A01958-40 |
|
A01935-40 |
|
A01936-40 |
|
A01951-40 |
|
A01952-40 |
|
A01885-40 |
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A01885-100 |
GenCrispr Cas9 Antibody, pAb, Rabbit - 100 µl |
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