Primary Antibodies


 


Primary Antibodies


Primary antibodies recognize and bind to unique epitopes with high affinity and specificity across a broad spectrum of biomolecules. They exist as high specificity monoclonal antibodies and/or as polyclonal antibodies. These antibodies are used for detecting specific biomolecules or measuring changes. GenScript offers over 1000 highly specific monoclonal and polyclonal primary antibodies, covering major areas of life science research, such as H1N1 Antibodies, Neuroscience Antibodies for Alzheimer's Parkinson's and Huntington's disease, Cytokine and Growth Factor Antibodies, Control Antibodies including isotype and loading control antibodies, Cell Marker Antibodies, and more. These primary antibodies are validated for multiple applications, including Sandwich ELISA and western blot.

GenScript also offers more than 200 cytokines, chemokines and growth factors, for your cell signaling and stem cell research demands with key features such as low endotoxin levels (<1.0 EU/μg) and high purity ( >95% ).

 

Immune Checkpoint Antibodies

 

Immune checkpoint-blocking antibodies that activate the immune system to fight cancer are becoming an important method of cancer treatment. CTLA-4 was the first immune checkpoint target and ipilimumab, an anti CTLA-4 antibody drug, was approved in 2011 for clinical use. The PD-1 receptor and its ligand PD-L1 have shown great promise as therapeutic targets in a variety of malignancies. The combined- target immunotherapy may have a higher level of effect in the future.

To facilitate this hot immunotherapy research field, GenScript provides immune checkpoint antibodies and immune checkpoint proteins for many kinds of applications. Products for more targets are coming in succession.

 

Application


  • Positive control for antibody drug early development
  • Validate cell line development
  • Facilitate assay development


Product List

Cat. No.

Product Name

A01974-40

Human 4-1BB Antibody (8C10), mAb, Mouse - 40 µg

A01964-40

Human CD27 Antibody (16G7), mAb, Mouse - 40 µg

A01874-40

Human CD38 Antibody (38.F2), mAb, Mouse - 40 ug

A01873-40

Human CD38 Antibody (38.H1), mAb, Mouse - 40 ug

A01973-40

Human CD80 Antibody (17F3), mAb, Mouse - 40 µg

A01982-40

Human CD86 Antibody (2B11), mAb, Mouse - 40 µg

A01832-40

Human CTLA-4 Antibody (CT.F3), mAb, Mouse - 40 ug

A01833-40

Human CTLA-4 Antibody (CT.E8), mAb, Mouse - 40 ug

A01842-40

Mouse CTLA-4 Antibody (MCT.F6), mAb, Mouse - 40 ug

A01843-40

Mouse CTLA-4 Antibody (MCT.F6), mAb, Mouse - 40 ug

A01959-40

Human HVEM Antibody (10C6), mAb, Mouse - 40 µg

A01875-40

Human LAG3 Antibody (LG.F9), mAb, Mouse - 40 ug

A01876-40

Human LAG3 Antibody (LG.B5), mAb, Mouse - 40 ug

A01866-40

Human OX40 Antibody (OX.A10), mAb, Mouse - 40 µg

A01867-40

Human OX40 Antibody (OX.E12), mAb, Mouse - 40 µg

A01828-40

Human PD-1 Antibody (PD1.H5), mAb, Mouse - 40 ug

A01829-40

Human PD-1 Antibody (PD1.D3), mAb, Mouse - 40 ug

A01830-40

Human PD-L1 Antibody (PDL1.D1), mAb, Mouse - 40 ug

A01831-40

Human PD-L1 Antibody (PDL1.A6), mAb, Mouse - 40 ug

A01981-40

Human TIGIT Antibody (20A9), mAb, Mouse - 40 µg

A01834-40

Human TIM3 Antibody (TI.B2), mAb, Mouse - 40 ug

A01835-40

Human TIM3 Antibody (TI.H3), mAb, Mouse - 40 ug

A01864-40

Human VISTA Antibody (VA.F6), mAb, Mouse - 40 µg

  

Anti-idiotype Antibody Products


Anti-idiotype antibodies (anti-ID Abs) are specific to the idiotype (variable region) of another antibody. This feature could be used to measure therapeutic antibody concentration in pre-clinical and clinical studies. An antibody response to the antibody drug might occur and result in devastating consequences in the body. Anti-idiotype antibodies are also commonly used as a reference standard for antibody drug immunogenicity(immune response, IR) studies.

Due to the approvals of the biosimilar products, patients could enjoy an affordable alternative to the innovator drugs. GenScript has generated various types of ready to use anti-idiotype antibodies against blockbuster drugs to support the development of biosimilars. We can also develop custom anti-idiotype antibody service for your new antibody drug development. Learn more »

 

Application


  • Pharmacokinetic (PK) studies: Used to measure the drug level in patient samples
  • Immunogenicity (anti-drug antibody, ADA) assays: Used as a positive control or reference standard


Features

 

Type

1. Antigen-blocking

2. Non-blocking

Schematic diagram

 

 

Feature

Paratope-specific

Not Paratope-specific

Antigen binding

Inhibitory

Not inhibitory

Application

Detect free drug only

Detect total drug (free and bound)


  • Anti-ID pairs available for sandwich ELISA
  • Broad detection range and accurate concentration result
  • MonoRab™ rabbit monoclonal antibody is perfect for picomolar-level immunoassay sensitivity
  •  
 





Schematic image of total Pembrolizumab or the biosimilar (free, partially bound, fully bound) PK study. The assay was developed by using Anti-Pembrolizumab Antibody, mAb, Mouse (Cat.No. A01844) as capture antibody and the biotin conjugated (Cat.No. A01845) as the detection antibody



Sensitivity

0.295 ng/ml

Detection Range

1.56-100 ng/ml

Test Samples

Human serum/plasma, mouse serum/plasma

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Schematic image of Pembrolizumab or the biosimilar immunogenicity assay. 

Anti-Pembrolizumab Antibody, pAb, Rabbit (Cat.No. A01846) can be used as positive control for the standard curve.


Sensitivity

0.20 ng/ml

Detection Range

1.56-100 ng/ml

Test Samples

Human serum/plasma (EDTA), mouse serum, rat serum/plasma (heparin), rabbit serum/plasma (heparin)


 


Affinity of MonoRab™ Anti-Pembrolizumab Antibody (90G12F8), mAb, Rabbit (Cat.No. A01853), Kd < 10-12M


Anti-Adalimumab/Humira® (Target‎: ‎TNF alpha)

Cat. No.

Product Name

Inhibitory IC50 (μg/ml)

Recommend Applications

A01954-40

Anti-Adalimumab Antibody (15C7), mAb, Mouse

0.258

Direct/Indirect/Inhibitory ELISA, 
Capture antibody for Adalimumab PK/PD bridging ELISA with A01955-40

A01955-40

Anti-Adalimumab Antibody (3C2), mAb, Mouse

Non-inhibitory

Direct/Indirect ELISA, 
Detection antibody for Adalimumab, PK/PD bridging ELISA with A01954-40

A01956-40

Anti-Adalimumab Antibody (3C2) [Biotin], mAb, Mouse

Non-inhibitory

Direct/Indirect ELISA, 
Detection antibody for Adalimumab, PK/PD bridging ELISA with A01954-40

A01886-40

Anti-Adalimumab Antibody, pAb, Rabbit

N/A

Direct ELISA, 
Immunogenicity assay

A01921-40

MonoRabᵀᴹ Anti-Adalimumab Antibody (4E12), mAb, Rabbit

0.175

Direct/Indirect/Inhibitory ELISA, 
Capture antibody for Adalimumab PK/PD bridging ELISA with A01922-40

A01922-40

MonoRabᵀᴹ Anti-Adalimumab Antibody (134D5), mAb, Rabbit

0.353

Direct/Indirect/Inhibitory ELISA, 
Detection antibody for Adalimumab, PK/PD bridging ELISA with A01921-40 

A01923-40

MonoRabᵀᴹ Anti-Adalimumab Antibody (196F3), mAb, Rabbit

Non-inhibitory

Direct ELISA, 
Immunogenicity assay


Anti-Atezolizumab/Tecentriq® (Target‎: ‎PD-L1)

Cat. No.

Product Name

Inhibitory IC50 (μg/ml)

Recommend applications

A01948-40

Anti-Atezolizumab Antibody (10G9), mAb, Mouse

0.118

Direct/Indirect/Inhibitory ELISA,
Capture antibody for Atezolizumab PK/PD bridging ELISA with A01949-40

A01949-40

Anti-Atezolizumab Antibody (6B12), mAb, Mouse

Non-inhibitory

Direct/Indirect ELISA, 
Detection antibody for Atezolizumab, PK/PD bridging ELISA with A01948-40

A01950-40

Anti-Atezolizumab Antibody (6B12) [Biotin], mAb, Mouse

Non-inhibitory

Direct/Indirect ELISA, 
Detection antibody for Atezolizumab, PK/PD bridging ELISA with A01948-40

A01984-40

MonoRab™ Anti-Atezolizumab Antibody (55D8) mAb, Rabbit

0.391

Direct/Indirect/Inhibitory ELISA,
Capture antibody for Atezolizumab PK/PD bridging ELISA with A01985-40

A01985-40

MonoRab™ Anti-Atezolizumab Antibody (43H11), mAb, Rabbit

0.847

Direct/Indirect ELISA, 
Detection antibody for Atezolizumab, PK/PD bridging ELISA with A01984-40

A01986-40

MonoRab™ Anti-Atezolizumab Antibody (43H11)[Biotin], mAb, Rabbit

0.847

Direct/Indirect ELISA, 
Detection antibody for Atezolizumab, PK/PD bridging ELISA with A01984-40


Anti-Bevacizumab/Avastin® (Target: VEGF-A)

Cat. No.

Product Name

Inhibitory IC50 (μg/ml)

Recommend applications

A01975-40

Anti-Bevacizumab Antibody (4H1), mAb, Mouse

N/A

Direct/Indirect ELISA, 
Capture antibody for Bevacizumab PK/PD bridging ELISA with A01976-40

A01976-40

Anti-Bevacizumab Antibody (6C3), mAb, Mouse

N/A

Direct/Indirect ELISA, 
Detection antibody for Bevacizumab, PK/PD bridging ELISA with A01975-40

A01977-40

Anti-Bevacizumab Antibody (6C3)[Biotin], mAb, Mouse

N/A

Direct/Indirect ELISA, 
Detection antibody for Bevacizumab, PK/PD bridging ELISA with A01975-40

A01887-40

Anti-Bevacizumab Antibody, pAb, Rabbit

N/A

Direct ELISA, 
Immunogenicity assay

A01895-40

MonoRabᵀᴹ Anti-Bevacizumab Antibody (30E1), mAb, Rabbit

Non-inhibitory

Direct/Indirect ELISA, 
Capture antibody for Bevacizumab, PK/PD bridging ELISA with A01896-40

A01962-40

MonoRabᵀᴹ Anti-Bevacizumab Antibody (46E3), mAb, Rabbit

0.046

Direct/Indirect/Inhibitory ELISA, 
Detection antibody for Bevacizumab, PK/PD bridging ELISA with A01895-40

A01896-40

MonoRabᵀᴹ Anti-Bevacizumab Antibody (46E3)[Biotin], mAb, Rabbit

0.046

Direct/Indirect/Inhibitory ELISA, 
Detection antibody for Bevacizumab, PK/PD bridging ELISA with A01895-40


Anti-Cetuximab/Erbitux® (Target: EGF receptor)

Cat. No.

Product Name

Inhibitory IC50 (μg/ml)

Recommend applications

A01938-40

Anti-Cetuximab Antibody (18D5), mAb, Mouse

0.2073

Direct/Indirect/Inhibitory ELISA, 
Detection antibody for Cetuximab, PK/PD bridging ELISA with A01939-40

A01939-40

Anti-Cetuximab Antibody (20H1), mAb, Mouse

Non-inhibitory

Direct/Indirect ELISA, 
Capture antibody for Cetuximab, PK/PD bridging ELISA with A01938-40

A01991-40

MonoRab™ Anti-Cetuximab Antibody (69H10), mAb, Rabbit

0.039

Direct/Indirect/Inhibitory ELISA, 
Capture antibody for Cetuximab, PK/PD bridging ELISA with A01992-40

A01992-40

MonoRab™ Anti-Cetuximab Antibody (90G3), mAb, Rabbit

0.015

Direct/Indirect/Inhibitory ELISA, 
Detection antibody for Cetuximab, PK/PD bridging ELISA with A01991-40

A01993-40

Anti-Cetuximab Antibody, pAb, Rabbit

N/A

Direct ELISA, 
Immunogenicity assay


Anti-Daratumumab/Darzalex® (Target: CD38)

Cat. No.

Product Name

Inhibitory IC50 (μg/ml)

Recommend applications

A01996-40

Anti-Daratumumab Antibody (11F2), mAb, Mouse

Non-inhibitory

Direct/Indirect ELISA, Capture antibody for Daratumumab, PK/PD bridging ELISA with A01997-40

A01997-40

Anti-Daratumumab Antibody (6A3), mAb, Mouse

0.582

Direct/Indirect/Inhibitory ELISA, 
Detection antibody for Daratumumab, PK/PD bridging ELISA with A01996-40

A01998-40

Anti-Daratumumab Antibody (9A6), mAb, Mouse

0.118

Direct/Inhibitory ELISA

A02009-40

MonoRab™ Anti-Daratumumab(139B10), mAb, Rabbit

0.017

Direct/Inhibitory ELISA


Anti-Durvalumab/Imfinzi® (Target: CD274)

Cat. No.

Product Name

InhibitoryIC50 (μg/ml)

Recommend applications

A02010-40

Anti-Durvalumab Antibody, pAb, Rabbit

N/A

Direct ELISA,Immunogenicity assay


Anti-Ipilimumab/Yervoy® (Target: CTLA-4)

Cat. No.

Product Name

Inhibitory IC50 (μg/ml)

Recommend applications

A01859-40

Anti-Ipilimumab Antibody(26B6H7D9), mAb, Mouse

Non-inhibitory

Direct/Indirect ELISA, 
Capture antibody for Ipilimumab, PK/PD bridging ELISA with A01858-40

A01961-40

Anti-Ipilimumab Antibody (4H6), mAb, Mouse

Non-inhibitory

Direct/Indirect ELISA, 
Detection antibody for Ipilimumab, PK/PD bridging ELISA with A01859-40

A01858-40

Anti-Ipilimumab Antibody (4H6)[Biotin], mAb, Mouse

Non-inhibitory

Direct/Indirect ELISA, 
Detection antibody for Ipilimumab, PK/PD bridging ELISA with A01859-40


Anti-Nivolumab/Opdivo® (Target‎: ‎PD-1)

Cat. No.

Product Name

Inhibitory IC50 (μg/ml)

Recommend applications

A01847-40

Anti-Nivolumab Antibody(8G6G3D8), mAb, Mouse

Non-inhibitory

Direct/Indirect ELISA, 
Capture antibody for Nivolumab, PK/PD bridging ELISA with A01848-40

A01965-40

Anti-Nivolumab Antibody (6G5), mAb, Mouse

Non-inhibitory

Direct/Indirect ELISA, 
Detection antibody for Nivolumab, PK/PD bridging ELISA with A01847-40

A01848-40

Anti-Nivolumab Antibody(6G6)[Biotin], mAb, Mouse

Non-inhibitory

Direct/Indirect ELISA, 
Detection antibody for Nivolumab, PK/PD bridging ELISA with A01847-40

A01931-40

Anti-Nivolumab Antibody, pAb, Rabbit

N/A

Direct ELISA, 
Immunogenicity assay

A01987-40

MonoRab™ Anti-Nivolumab Antibody (33H4), mAb, Rabbit

0.484

Direct/Indirect ELISA, 
Capture antibody for Nivolumab, PK/PD bridging ELISA with A01988-40 

A01988-40

MonoRab™ Anti-Nivolumab Antibody (40F11), mAb, Rabbit

0.171

Direct/Indirect/Inhibitory ELISA, 
Detection antibody for Nivolumab, PK/PD bridging ELISA with A01987-40

A01989-40

MonoRab™ Anti-Nivolumab Antibody (40F11)[Biotin], mAb, Rabbit

0.171

Direct/Indirect/Inhibitory ELISA, 
Detection antibody for Nivolumab, PK/PD bridging ELISA with A01987-40

A01990-40

MonoRab™ Anti-Nivolumab Antibody (47F6), mAb, Rabbit

0.104

Direct/Inhibitory ELISA


Anti-Obinutuzumab/Gazyva® (Target: CD20)

Cat. No.

Product Name

Inhibitory
IC50 (μg/ml)

Recommend applications

A01945-40

Anti-Obinutuzumab Antibody (18H8), mAb, Mouse

N/A

Direct/Indirect ELISA, 
Capture antibody for Obinutuzumab PK/PD bridging ELISA with A01946-40

A01946-40

Anti-Obinutuzumab Antibody (16B7), mAb, Mouse

N/A

Direct/Indirect ELISA, 
Detection antibody for Obinutuzumab, PK/PD bridging ELISA with A01945-40

A01947-40

Anti-Obinutuzumab Antibody (16B7) [Biotin], mAb, Mouse

N/A

Direct/Indirect ELISA, 
Detection antibody for Obinutuzumab, PK/PD bridging ELISA with A01945-40

A01933-40

Anti-Obinutuzumab Antibody, pAb, Rabbit

N/A

Direct ELISA, 
Immunogenicity assay

A01966-40

MonoRabᵀᴹ Anti-Obinutuzumab Antibody (8G12), mAb, Rabbit

N/A

Direct/Indirect ELISA, 
Capture antibody for Obinutuzumab PK/PD bridging ELISA with A01967-40

A01967-40

MonoRabᵀᴹ Anti-Obinutuzumab Antibody (169F10), mAb, Rabbit

N/A

Direct/Indirect ELISA, 
Detection antibody for Obinutuzumab, PK/PD bridging ELISA with A01966-40

A01968-40

MonoRabᵀᴹ Anti-Obinutuzumab Antibody (169F10) [Biotin], mAb, Rabbit

N/A

Direct/Indirect ELISA, 
Detection antibody for Obinutuzumab, PK/PD bridging ELISA with A01966-40


Anti-Pembrolizumab/Keytruda® (Target: PD-1)

Cat. No.

Product Name

Inhibitory IC50 (μg/ml)

Recommend applications

A01844-40

Anti-Pembrolizumab Antibody(1D6E10), mAb, Mouse

Non-inhibitory

Direct/Indirect ELISA,
Capture antibody for pembrolizumab, PK/PD bridging ELISA with A01845

A01845-40

Anti-Pembrolizumab Antibody(10E12C6)[Biotin], mAb, Mouse

0.37

Direct/Indirect/Inhibitory ELISA, 
Detection antibody for pembrolizumab, PK/PD bridging ELISA with A01844

A01846-40

Anti-Pembrolizumab Antibody, pAb, Rabbit

N/A

Direct ELISA, 
Immunogenicity assay

A01960-40

MonoRabᵀᴹ Anti-Pembrolizumab Antibody (90G12), mAb, Rabbit 

0.38

Direct/Inhibitory ELISA

A01853-40

MonoRab™ Anti-Pembrolizumab Antibody(90G12)[Biotin], mAb, Rabbit

0.38

Direct/Inhibitory ELISA

A02007-40

MonoRab™ Anti-Pembrolizumab Antibody (47E5), mAb, Rabbit

0.009

Direct/Indirect/Inhibitory ELISA,
Detection antibody for Pembrolizumab,
PK/PD bridging ELISA with A02008

A02008-40

MonoRab™ Anti-Pembrolizumab Antibody (94B9), mAb, Rabbit

0.580

Direct/Indirect ELISA
Capture antibody for Pembrolizumab, PK/PD bridging ELISA with A02007

L00696

Pembrolizumab ELISA Detection Kit


Anti-Rituximab/Rituxan® (Target‎: ‎CD20)

Cat. No.

Product Name

Inhibitory IC50 (μg/ml)

Recommend applications

A01969-40

Anti-Rituximab Antibody (6C1), mAb, Mouse

N/A

Direct/Indirect ELISA, 
Capture antibody for Rituximab, PK/PD bridging ELISA with A01970-40

A01970-40

Anti-Rituximab Antibody (17B6), mAb, Mouse

N/A

Direct/Indirect ELISA, 
Detection antibody for Rituximab, PK/PD bridging ELISA with A01969-40

A01971-40

Anti-Rituximab Antibody (17B6)[Biotin], mAb, Mouse

N/A

Direct/Indirect ELISA, 
Detection antibody for Rituximab, PK/PD bridging ELISA with A01969-40

A01918-40

Anti-Rituximab Antibody, pAb, Rabbit

N/A

Direct ELISA, 
Immunogenicity assay

A01942-40

MonoRabᵀᴹ Anti-Rituximab Antibody (137C6), mAb, Rabbit

N/A

Direct/Indirect ELISA, 
Capture antibody for Rituximab, PK/PD bridging ELISA with A01943-40

A01943-40

MonoRabᵀᴹ Anti-Rituximab Antibody (194D7), mAb, Rabbit

N/A

Direct/Indirect ELISA, 
Detection antibody for Rituximab, PK/PD bridging ELISA with A01942-40

A01944-40

MonoRabᵀᴹ Anti-Rituximab Antibody (194D7)[Biotin], mAb, Rabbit

N/A

Direct/Indirect ELISA, 
Detection antibody for Rituximab, PK/PD bridging ELISA with A01942-40


Anti-Tocilizumab/Actemra® (Target: IL-6 receptor)

Cat. No.

Product Name

Inhibitory IC50 (μg/ml)

Recommend applications

A01978-40

Anti-Tocilizumab Antibody (14B10), mAb, Mouse

N/A

Direct/Indirect ELISA, 
Capture antibody for Tocilizumab PK/PD bridging ELISA with A01979-40

A01979-40

Anti-Tocilizumab Antibody (6C10), mAb, Mouse

N/A

Direct/Indirect ELISA, 
Detection antibody for Tocilizumab, PK/PD bridging ELISA with A01978-40

A01980-40

Anti-Tocilizumab Antibody (6C10)[Biotin], mAb, Mouse

N/A

Direct/Indirect ELISA, 
Detection antibody for Tocilizumab, PK/PD bridging ELISA with A01978-40

A01932-40

Anti-Tocilizumab Antibody, pAb, Rabbit

N/A

Direct ELISA, Immunogenicity assay

 

Neuroscience Antibodies


The discovery of new potential drug targets, signaling molecules and structural proteins in the brain has dramatically increased the demand for high-quality neuroscience antibodies. The research on traditional targets and pathways will continue to focus on dopamine, beta amyloid, and serotonin. GenScript offers a wide range of tools, including pan and phospho-specific antibodies as well as peptides and proteins geared toward different areas of neuroscience research. These antibodies, particularly those applicable to studies involving various pathways leading to neurological diseases, are among the bio-reagents keenly sought by neuroscience researchers.

All GenScript's neuroscience antibodies are carefully purified prior to delivery. Most of our production processes involve affinity chromatography purification based on the relevant epitope, further ensuring the quality of antibodies. GenScript has a comprehensive collection of antibodies targeting Alzheimer's disease and other neurological diseases including Parkinson's disease, Huntington's disease, and amyotrophic lateral sclerosis.

 

Key Features


  • Unique collection of phospho-specific antibodies and their non-phospho pairs
  • Full coverage of neurological disease pathways
  • Multiple applications: Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC), ELISA, etc.

 

Alzheimer's Disease Antibodies

 

Tau Protein

Cat. No.

Product Name

A01387-40

Tau Antibody (Ser396), pAb, Rabbit - 40 ug

A01100-40

Tau Antibody (Phospho-Thr205), pAb, Rabbit - 40 ug

A01099-40

Tau Antibody (Ser262), pAb, Rabbit - 40 ug

A01096-40

Tau Antibody (Phospho-Ser235), pAb, Rabbit - 40 ug

A01051-40

Tau Antibody (Ser422), pAb, Rabbit - 40 ug

A01048-40

Tau Antibody (Ser356), pAb, Rabbit - 40 ug

A00942-40

Tau Antibody (Ab-217), pAb, Rabbit - 40 ug

A00900-40

Tau Antibody (Phospho-Ser422), pAb, Rabbit - 40 ug

A00899-40

Tau Antibody (Phospho-Ser409), pAb, Rabbit - 40 ug

A00898-40

Tau Antibody (Phospho-Ser400), pAb, Rabbit - 40 ug

A00896-40

Tau Antibody (Phospho-Thr217), pAb, Rabbit - 40 ug

A00894-40

Tau Antibody (Phospho-Ser199), pAb, Rabbit - 40 ug

  

APP

Cat. No.

Product Name

A00696-40

Amyloid Precursor Protein Antibody (747-761), pAb, Rabbit - 40 ug

A00695-40

Amyloid Precursor Protein Antibody (671-685), pAb, Rabbit - 40 ug

A00694-40

Amyloid Precursor Protein Antibody (653-662), pAb, Rabbit - 40 ug

  

β-Secretase Antibodies

Cat. No.

Product Name

A00878-40

BACE1 Antibody (26-45), pAb, Rabbit - 40 ug

A00880-40

BACE1 Antibody (485-501), pAb, Rabbit - 40 ug

  

γ-Secretase Antibodies

Cat. No.

Product Name

A00883-40

Nicastrin Antibody, pAb, Rabbit - 40 ug

A00881-40

Presenilin 1 Antibody, pAb, Rabbit - 40 ug

A00882-40

PEN2 Antibody, pAb, Rabbit - 40 ug

  

GSK3 Synuclein Catenins

Cat. No.

Product Name

A01235-40

β-Catenin Antibody, pAb, Rabbit - 40 ug

  

Beta-Amyloid

Cat. No.

Product Name

A00685-40

β-Amyloid Antibody (1-17), pAb, Rabbit - 40 ug

A00685-100

β-Amyloid Antibody (1-17), pAb, Rabbit - 100 ug

A00687-40

β-Amyloid Antibody (25-35), pAb, Rabbit - 40 ug

A00688-40

β-Amyloid Antibody (1-40), pAb, Rabbit - 40 ug

A01566

Human β-Amyloid 1-40 Antibody (4A4F2), mAb, Mouse - 100 ug

A01567-40

Human β-Amyloid 1-42 Antibody (2C2G5), mAb, Mouse - 40 ug

  

Neuronal Markers

Cat. No.

Product Name

A01189-40

Vimentin Antibody, pAb, Rabbit - 40 ug

A01268-40

Calbindin Antibody, pAb, Rabbit - 40 ug

A01302-40

Rab5 Antibody, pAb, Rabbit - 40 ug

A01303-100

Doublecortin Antibody, pAb, Rabbit - 100 ug

A01307-40

Synaptophysin Antibody, pAb, Rabbit - 40 ug

A01308-40

CNPase Antibody, pAb, Rabbit - 40 ug

A01309-40

GFAP Antibody, pAb, Rabbit - 40 ug

A01398-40

PGP9.5 Antibody, pAb, Rabbit - 40 ug

A01405-40

NSE Antibody, pAb, Rabbit - 40 ug

 

Other diseases

 

Parkinson's disease

Cat. No.

Product Name

A01250-40

Parkin Antibody, pAb, Rabbit - 40 ug

A01268-40

Calbindin Antibody, pAb, Rabbit - 40 ug

A01398-40

PGP9.5 Antibody, pAb, Rabbit - 40 ug

  

Amyotrophic lateral sclerosis (ALS)

Cat. No.

Product Name

A01005-40

Superoxide Dismutase 1 Antibody, pAb, Rabbit - 40 ug

 

Examples

 

Western blot analysis of recombinant human Tau protein using Tau Antibody (Phospho-Ser422), pAb, Rabbit (GenScript, A01051)




<!--[endif]-->

Lane 1: Tau Antibody (Ser422) pre-incubated with non-phoshpo-peptide

Lane 2: Tau Antibody (Ser422) pre-incubated with phoshpo-peptide

Lane 3: Tau Antibody (Ser422)

Lane 4: Rabbit IgG Control

Secondary Antibody: Goat Anti Rabbit IgG (H&L) [HRP] (GenScript, A00098)

The signal was developed with LumiSensor™ HRP Substrate Kit (GenScript, L00221V500)  

 

 

 

 

 

Western blot analysis of human β-Amyloid (1-40) and β-Amyloid (1-42) peptides using β-Amyloid Antibody (1-17), pAb, Rabbit (GenScript, A00685)




<!--[endif]-->




Secondary Antibody: Goat Anti Rabbit IgG (H&L) [HRP] (GenScript, A00098)

The signal was developed with LumiSensor™ HRP Substrate Kit (GenScript, L00221V500)

 

 

 

 

 


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  • THE™ Elite Antibodies: THE™ stands for THE unmistakable, THE irreplaceable, and THE best quality in the industry. GenScript is proud to present THE™ Elite Antibody series, the most precise and effective antibodies in the market, meeting requirements of even the strictest research.
  • H1N1 Antibodies: High quality antibodies can be readily employed in the detection of influenza A virus (H1N1) through routine immunoassays.
  • β-Amyloid Peptides: GenScript's FlexPeptide™ peptide synthesis platform allows us to synthesize a comprehensive array of human and rat beta amyloid peptide fragments covering stretches of its amino acid sequence. This can ease the process of elucidating the potential biological interactions of each specific fragment.
  • ONE-HOUR Western™ Kits: The ONE-HOUR Western™ Kits are a series of new products that cut the total procedure time of a Western or dot blot from 4.5 hours to ONE hour with no loss in sensitivity. GenScript's scientists are continuously searching for ways to improve technology and reduce costs. Recently we upgraded to 2nd generation ONE-HOUR Western technology to give you even higher sensitivity and lower background of your Westerns in ONE hour.
  • Custom Antibody Services: Reliable immunological assay demands reliable antibodies. Thus reliable antibody services are crucial. GenScript provides one-stop solution to all our customers' antibody needs.
  • Custom Peptide Services: Peptides are often used as tools in functional assays and antibody production, particularly in drug discovery. GenScript's peptide synthesis services include standard and express chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression

 

Control Antibodies

 

Isotype Control Antibodies

The selection of an appropriate isotype control is key for flow cytometry experiments. Isotype control antibodies that have no relevant specificity can distinguish non-specific "background" staining from specific antibody staining. Three main factors contribute to the levels of background staining associated with a primary antibody: a) binding to Fc receptors on target cells, b) non-specific protein interactions with cellular proteins, lipids, or carbohydrates, and c) cell autofluorescence. All of these factors vary greatly depending on the target cell type and the isotype of the primary antibody. Therefore, in order to accurately determine the level of specific staining by the primary antibody, isotype controls need to be matched to the specific primary antibodies being used. GenScript offers a series of isotype control antibodies that can be used in your research.

 

Loading Control Antibodies

Loading control proteins are known to be constitutively and stably expressed at high levels in almost all tissues and cells. Housekeeping proteins, such as GAPDH, tubulin, and actin, represent some of the well-known loading control proteins.

 

Loading control antibodies are used in Western blotting for two main purposes:

  1. To estimate relative amounts of total protein loaded in each lane. (This information is needed to determine if the difference in levels of the protein of interest in different samples is due to loading and transfer errors or to real changes in protein expression.)
  2. To troubleshoot the Western blotting procedure.

 

GenScript offers a wide selection of polyclonal and monoclonal loading control antibodies for GAPDH, α-tubulin, and β-actin for several species. HRP- and biotin-conjugated versions of these antibodies are also available.

 

Isotype Control Antibodies

Cat. No.

Product Name

A01010

Chicken IgY Control (Whole Molecule), Purified - 4 mg

A01009

Goat IgG Control (Whole Molecule), Purified - 4 mg

A02005

Guinea pig IgG control (Whole Molecule), Purified - 1 mg

A01006

Human IgG Control(Whole Molecule), Purified - 4 mg

A01383

Human IgG Control [FITC] (Whole Molecule), Purified - 0.5 mg

A01007

Mouse IgG control (Whole Molecule), Purified - 1 mg

A01381

Mouse IgG Control [FITC] (Whole Molecule), Purified - 0.5 mg

A01011

Mouse IgG1 control (Whole Molecule), Purified - 1 mg

A02000

Mouse IgG2a control (Whole Molecule), Purified - 1 mg

A01730

Mouse IgG2b control (Whole Molecule), Purified - 1 mg

A01008

Rabbit IgG Control (Whole Molecule), Purified - 4 mg

A01382

Rabbit IgG Control [FITC] (Whole Molecule), Purified - 0.5 mg

A02004

Rat IgG control (Whole Molecule), Purified - 1 mg

  

Loading Control Antibodies

Cat. No.

Product Name

A01865-40

MonoRabᵀᴹ Beta Actin Antibody, mAb, Rabbit - 40 µg

A00702-40

THETM beta Actin Antibody, mAb, Mouse - 40 ug

A00702-200

THETM beta Actin Antibody, mAb, Mouse - 200 ug

A00702-100

THETM beta Actin Antibody, mAb, Mouse - 100 ug

A00730-200

THETM beta Actin Antibody [HRP], mAb, Mouse - 200 ug

A00730-100

THETM beta Actin Antibody [HRP], mAb, Mouse - 100 ug

A01546

THETM beta Actin Antibody [Biotin], mAb, Mouse - 100 ug

A01410-40

THETM alpha Tubulin Antibody, mAb, Mouse - 40 ug

A01410-100

THETM alpha Tubulin Antibody, mAb, Mouse - 100 ug

A01490

THETM alpha Tubulin Antibody [HRP], mAb, Mouse - 100 ug

A01545

THETM alpha Tubulin Antibody [Biotin], mAb, Mouse - 100 ug

A00885-40

α-Actin-1 Antibody, pAb, Rabbit - 40 ug

A00885-200

α-Actin-1 Antibody, pAb, Rabbit - 200 ug

A01203-40

β-Tubulin III Antibody, pAb, Rabbit - 40 ug

A01622-40

GAPDH Antibody, mAb, Mouse - 40 ug

A00191-40

GAPDH Antibody, pAb, Goat - 40 ug

A00192-40

GAPDH Antibody [HRP], pAb, Goat - 40 ug

A00915-40

GAPDH Antibody [Biotin], pAb, Goat - 40 ug

A01419-40

VDAC1 Antibody, pAb, Rabbit - 40 ug

A01717-40

β-tubulin Antibody (2G7D4), mAb, Mouse - 40 ug

 

Examples:

 

1. Sensitivity Comparison



<!--[endif]-->Primary Antibody:

  1. 0.1 μg/ml THE™ β-Actin mAb(Mouse)(GenScript, A00702)
  2. 0.1 μg/ml β-Actin mAb (Mouse) (Company X)

Secondary Antibody:

  • Goat Anti-Mouse IgG (H&L) [HRP] pAb (GenScript, 1:10,000, A00160)
  • The signal was developed with Lumisensor™ HRP Substrate Kit (GenScript, L00221V500)

 

 

 

 

2. Immunofluenrescence Analysis


 

<!--[endif]-->Primary Antibody:

  • 0.1 μg/ml THE™ β-Tubulin mAb (GenScript, A01410)

Secondary Antibody:

  • Fluorescein conjugated affinity purified anti-Mouse IgG (H&L) (Goat) (Rockland, 1:1,000, 610-102-121)






<!--[endif]-->3. Fluorescence Western Blotting


 

Primary Antibody:

  • 0.1 μg/ml GAPDH Antibody, pAb, Goat (GenScript, A00191)

Lane 1-8:

  • 5.0, 2.5,1.25, 0.62, 0.31, 0.16, 0.08 and 0.04 μg of Hela cell lysate
  • The signal was developed with One-Step Western™ Fluorescent Kit (GenScript, L00397)

 

 

Phospho Specific Antibodies


Phosphorylation/dephosphorylation is one of the major signaling mechanisms used to modulate the functional properties of proteins involved in gene expression, cell adhesion, cell proliferation, cell differentiation, and the cell cycle. The determination of the state of phosphorylation is highly important for studying the function of a given protein. Phospho-specific antibodies, which can discriminate between the phosphorylated and non-phosphorylated forms, have emerged as demonstrated assets in the study of signal transduction pathways. These novel tools enable qualitative and quantitative detection of phosphorylated proteins without the risks associated with using radioactivity.

 

GenScript's phospho-specific antibodies are affinity-purified and do not cross react with non-phosphorylated forms of proteins. Phospho-specific antibodies detect only the phosphorylated forms of proteins in a complex protein mixture within cells. They recognize the phosphorylated amino acids in the context of the surrounding amino acid sequence. Using a combination of pan-antibody (that recognizes both phosphorylated and non-phosphorylated forms of the protein) and phospho-specific antibody, it is possible to assess the degree of phosphorylation for any given protein.

 

GenScript offers phospho-specific/pan antibody pairs that are suitable for many tasks, including Western blot analysis, ELISA, and immunocytochemical assays. We also provide blocking peptides for most of our phospho-specific and pan antibodies. These peptides can be used to confirm that the observed signal is due to the antibody's interaction with target antigen, as opposed to non-specific binding.

 

Ordering information

 

Cat. No.

Product Name

A01819-100

THETM Phosphotyrosine Antibody (E10)plus - 100 ug

A01818-100

Phosphotyrosine Antibody (18E10), mAb, Mouse - 100 ug

A01817-100

Phosphotyrosine Antibody (5E10), mAb, Mouse - 100 ug

A01634-40

RNA Polymerase II CTD Repeat Antibody (Phospho-Ser5), pAb, Rabbit - 40 ug

A01633-40

RNA polymerase II CTD repeat Antibody (Phospho-Ser2), pAb, Rabbit - 40 ug

A01633-200

RNA polymerase II CTD repeat Antibody (Phospho-Ser2), pAb, Rabbit - 200 ug

A01100-40

Tau Antibody (Phospho-Thr205), pAb, Rabbit - 40 ug

A01096-40

Tau Antibody (Phospho-Ser235), pAb, Rabbit - 40 ug

A00965-40

Akt Antibody (Phospho-Ser473), pAb, Rabbit - 40 ug

  

Cat. No.

Product Name

A00900-40

Tau Antibody (Phospho-Ser422), pAb, Rabbit - 40 ug

A00899-40

Tau Antibody (Phospho-Ser409), pAb, Rabbit - 40 ug

A00898-40

Tau Antibody (Phospho-Ser400), pAb, Rabbit - 40 ug

A00896-40

Tau Antibody (Phospho-Thr217), pAb, Rabbit - 40 ug

A00894-40

Tau Antibody (Phospho-Ser199), pAb, Rabbit - 40 ug

A00727-40

Chk1 Antibody (Phospho-Ser296), pAb, Rabbit - 40 ug

A00697-40

APP Antibody (Phospho-Tyr757), pAb, Rabbit - 40 ug

 

H1N1 Flu Antibodies


Influenza A (H1N1) virus, a subtype of influenza virus A, is the most common cause of influenza in humans. A strain of swine-origin H1N1 was responsible for the 2009 flu pandemic. On April 29th, 2009, the influenza pandemic alert of H1N1 flu was raised from phase 4 to phase 5. Subsequently on June 11th, 2009, the alert progressed to phase 6 as announced by WHO. In response to this severe situation, GenScript will offer whatever resources available to help researchers contain H1N1 virus.

At GenScript, we produce high-quality bio-reagents, including highly sensitive and specific antibodies, genes, peptides, and proteins, in a flexible and timely manner. Specifically, high quality antibodies can be readily employed in the detection of influenza A virus through routine immunoassays (Western blotting). Various epitope antibodies are also available for virus characterization. Please select the H1N1 antibody you would like to place your order!

 

Cat. No.

Product Name

A01500-40

H1N1 HA antibody, pAb, Rabbit - 40 ug

A01500-100

H1N1 HA antibody, pAb, Rabbit - 100 ug

A01557-40

H1N1 HA Antibody, pAb, Rabbit - 40 ug

A01557-100

H1N1 HA Antibody, pAb, Rabbit - 100 ug

A01553-100

H1N1 NA Antibody, pAb, Rabbit - 100 ug

A01499-40

H1N1 NS2 antibody, pAb, Rabbit - 40 ug

A01499-100

H1N1 NS2 antibody, pAb, Rabbit - 100 ug

A01551-40

H1N1 NS1 Antibody, pAb, Rabbit - 40 ug

A01506-40

H1N1 NP Antibody, pAb, Rabbit - 40 ug

A01464-40

H1N1 PB2 Antibody, pAb, Rabbit - 40 ug

A01464-100

H1N1 PB2 Antibody, pAb, Rabbit - 100 ug

A01465-40

H1N1 PA Antibody, pAb, Rabbit - 40 ug

A01465-200

H1N1 PA Antibody, pAb, Rabbit - 200 ug

A01467-40

H1N1 PB1 antibody, pAb, Rabbit - 40 ug

  

Cell Marker/Cell Surface Antigen Antibodies


Cell markers, also known as cell surface antigens, serve as monograms to help identify and classify cells. The majority of them are molecules or antigens within cell's plasma membrane. Unique to different cell types, there exist specific combinations of markers or antigens. These molecules serve not only as markers but they also have key functional roles. It is possible to diagnose diseases or direct treatment by identifying which molecules are present.


GenScript offers a wide variety of antibodies relevant to cell markers/cell surface antigens of various species, including human, mouse, and more.

Cat. No.

Product Name

A00678-40

EB1 Antibody, pAb, Rabbit - 40 ug

A01308-40

CNPase Antibody, pAb, Rabbit - 40 ug

A01434-40

PDI Antibody, pAb, Rabbit - 40 ug

A01455-40

Lamin A+C Antibody, pAb, Rabbit - 40 ug

A01455-100

Lamin A+C Antibody, pAb, Rabbit - 100 ug

A01462-40

Fibrillarin Antibody, pAb, Rabbit - 40 ug

A01495-40

Ki-67 Antibody, pAb, Rabbit - 40 ug

A01507-40

Cytochrome C Antibody, pAb, Rabbit - 40 ug

A01510-40

GRP94 Antibody, pAb, Rabbit - 40 ug

A01513-40

C-Fos Antibody, pAb, Rabbit - 40 ug

A01514-40

EEA1 antibody, pAb, Rabbit - 40 ug

A01514-100

EEA1 antibody, pAb, Rabbit - 100 ug

A01596-40

SCF antibody, pAb, Rabbit - 40 ug

A01596-100

SCF antibody, pAb, Rabbit - 100 ug

A01189-40

Vimentin Antibody, pAb, Rabbit - 40 ug

A01191-40

Vimentin Antibody, pAb, Rabbit - 40 ug

A01191-100

Vimentin Antibody, pAb, Rabbit - 100 ug

A01193-40

Vimentin Antibody, pAb, Rabbit - 40 ug

A01413-40

Nestin Antibody, pAb, Rabbit - 40 ug

A01415-40

NCAM Antibody, pAb, Rabbit - 40 ug

A01415-100

NCAM Antibody, pAb, Rabbit - 100 ug

A01781-40

CD90 Antibody (5A4D10), mAb, Rat - 40 ug

  

Related Products

Cat. No.

Product Name

A00191-40

GAPDH Antibody, pAb, Goat - 40 ug

A00192-40

GAPDH Antibody [HRP], pAb, Goat - 40 ug

A00702-40

THETM beta Actin Antibody, mAb, Mouse - 40 ug

A00702-200

THETM beta Actin Antibody, mAb, Mouse - 200 ug

A00702-100

THETM beta Actin Antibody, mAb, Mouse - 100 ug

A00730-200

THETM beta Actin Antibody [HRP], mAb, Mouse - 200 ug

A00730-100

THETM beta Actin Antibody [HRP], mAb, Mouse - 100 ug

A00915-40

GAPDH Antibody [Biotin], pAb, Goat - 40 ug

A00885-40

α-Actin-1 Antibody, pAb, Rabbit - 40 ug

A00885-200

α-Actin-1 Antibody, pAb, Rabbit - 200 ug

A01203-40

β-Tubulin III Antibody, pAb, Rabbit - 40 ug

A01410-40

THETM alpha Tubulin Antibody, mAb, Mouse - 40 ug

A01410-100

THETM alpha Tubulin Antibody, mAb, Mouse - 100 ug

A01490

THETM alpha Tubulin Antibody [HRP], mAb, Mouse - 100 ug

 

GPCR Antibodies


G protein-coupled receptors (GPCRs) are found only in eukaryotes, including yeast, plants, choanoflagellates, and animals. They constitute a large protein family of transmembrane receptors that have the ability to sense molecules outside the cell and activate intracellular signal transduction pathways resulting in a variety of cellular responses. The ligands that bind and activate these receptors vary in size from small molecules to large proteins and include light-sensitive compounds, odors, pheromones, hormones and neurotransmitters. GPCRs are involved in many types of disease and serve as targets for almost half of all modern medicinal drugs. 

GenScript offers a wide selection of antibodies to help accelerate your GPCR research.

Cat. No.

Product Name

A00614-40

cAMP Antibody, pAb, Rabbit - 40 μl

A00615-40

cGMP Antibody, pAb, Rabbit - 40 μl

A00615-200

cGMP Antibody, pAb, Rabbit - 200 μl

A00993-40

CXCR2 Antibody, pAb, Rabbit - 40 ug

A00995-100

CXCR4 Antibody, pAb, Rabbit - 100 ug

A01074-40

GPR30 Antibody, pAb, Rabbit - 40 ug

A01316-40

ADP Antibody, pAb, Rabbit - 40 μl

A01316-200

ADP Antibody, pAb, Rabbit - 200 μl

A01424-40

DARPP-32 Antibody, pAb, Rabbit - 40 ug

A01589-40

E-Cadherin antibody, pAb, Rabbit - 40 ug

A01591-40

SSTR2 antibody, pAb, Rabbit - 40 ug

A01591-100

SSTR2 antibody, pAb, Rabbit - 100 ug

A01826-40

GLP1R Antibody, mAb, Mouse - 40 ug

 

Cytokine and Growth Factor Antibodies


Cytokines and growth factors are a category of signaling molecules active in cellular communication. They are proteins of vital importance to the development and function of both the innate and adaptive immune response. Cytokines and growth factors are often secreted by immune cells that have encountered a pathogen, thereby activating and recruiting further immune cells to enhance the immune response. Cytokines and growth factors are also involved in several developmental processes during embryogenesis.

GenScript offers a wide selection of antibodies that can be used in your cytokine and growth factor research. We offer various capture and detection antibody pairs for your quantitative ELISAs.

 

Cat. No.

Product Name

A00044-500

IL-8 Antibody, mAb, Mouse - 500 ug

A00044-100

IL-8 Antibody, mAb, Mouse - 100 ug

A01897-40

Human IFN-γ Antibody (16F3) [Biotin], mAb, Mouse - 40 µg

A01898-40

Human IFN-γ Antibody (21G2), mAb, Mouse - 40 µg

  

Related Products

Cat. No.

Product Name

A00614-40

cAMP Antibody, pAb, Rabbit - 40 μl

A00615-40

cGMP Antibody, pAb, Rabbit - 40 μl

A00615-200

cGMP Antibody, pAb, Rabbit - 200 μl

A00993-40

CXCR2 Antibody, pAb, Rabbit - 40 ug

A00995-100

CXCR4 Antibody, pAb, Rabbit - 100 ug

 

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